well that is another story. at minimum you will have to consider how you will mill them - which will determine how you can design them.
in dentmill you need to have the interface premilled, and the interface of the stl removed, which makes design actually kinda easy; considering theres no need for a base in the stl data you could design something to interface with the analog on the scan model, like a healing cap, and work from a fixed plane upwards.
if you intend on milling ti on a haas, milling the full interface, you'll need to pay for the implant module, no getting around that. not that i can noodle without more practice.
well, unless you do a physical waxup using something like a burnout cap, that interfaces with the model correctly.
scan the waxup in its fully sprued orientation, add the hole... call it an attachment that cannot be resized (a flick of a control panel setting) and add it to anything... but that's already too much work. far faster to use the implant tools.