The iModela has been quite a big hit with the "Maker" crowd. I have one at home and my kids love it! They were designing from day one with the included CAD/CAM software and making parts in wood, foam and wax.
Not for labs or industrial use but for home use by hobbyists its a winner!
Here is a picture that shows custom wheels that were made for a 240Z scale model. The wax patterns were cut from wax on the iModela, silicon molds were made from the patterns and urethane castings were used to create a set of wheels for the model car.