Tell your wife the sewing room does not pay the bills.
Unless your looking to grow and bring in employees stay put.
John brings up a great point...I just did this not too long ago. There is no way in hell i'd move without making sure I had the bank account looking REAL good. Also, no way I would lease or rent either. There is so many commericial pieces of shlt out there for practically nothing. I only highly suggest this because...
1. You could make it fun with your family---searching for a new place, renovating a place that will be yours, having family (contractors) help you build it.
2. Your accountant will want you to buy as well...the lab will pay you rent
3. If you want to add-on, or slow down, go for it...your overhead is minimal, you own the place.
4. A lot of the household bills are wrote off currently because your business is in the house...this will change, so be prepared.
5. You can take your time building and renovating when you own it...pace yourself, and pace your bank account, you only move when everything is done, you've made the bank account swell, and are ready to do it.
6. Seriously, it can be the most rewarding thing to do, but do it smart or you'll be regretting it very shortly.
I updated my website (below) recently to include some pictures/video of the lab...have a look. It all started from the kitchen table 7 years ago.