i run a 4mm 1flute roughing tool 135m/min, 0.15 mm Fz, around 1600mm/min feed.
2mm 126m/min, 0.05 Fz, 2000 mm/min feed
1mm 79m/min 0.05 Fz, 2500 mm/min feed.
the exact choice of toolpaths and engagements to accomplish my milling time i keep to myself, but this is about middle of the road for safe cutting, because it is good for pmma, wax, peek, zirconia, acetal and virtually all soft materials.
you need to go fast through soft materials. this (1mm @ 2500mm/min) is faster than some machines can go, but safe for the good imes mills (350+)
i chew through a 25mm full arch denture in just over 2 hours. more if the part has lots of holes or undercuts. i'm working on a method to reduce that by at least 30%
for peek and polycarbonate you want to mill wet. for acetal use air, i prefer milling pmma wet due to improved surface finish. dry tends to cut rough and break tools, even with air. plus the static is bad. so for me wet is good.