JMN
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In Science Advances Jan '19 issue they publish a study which shows that, in mice, the bacteria Porphyromans gingivalis (the same bacteria that causes much chronic gingivitis) produced toxins called 'Gingipains', the bacteria and the toxin were both found in the brain of subjects with oral bacterial load. Administering gingipain inhibitors showed a reduction in neuroinflamation, and the bacterial colony in the brain as well.
Short version: The more oral bacteria, the greater it's toxins, and with the bacterial P. Gingivalis there is proof it and it's toxins have part of causing the brain 'plaques' in Alzheimer's patients.
They found a treatment which was effective in reducing the infection and toxins that were in the brain.
Article:
https://www.sciencealert.com/new-evidence-reveals-an-unexpected-culprit-behind-alzheimer-s-disease
The Study:
Http://advances.sciencemag.org/content/5/1/eaau3333
Edit: Can't seplll
Short version: The more oral bacteria, the greater it's toxins, and with the bacterial P. Gingivalis there is proof it and it's toxins have part of causing the brain 'plaques' in Alzheimer's patients.
They found a treatment which was effective in reducing the infection and toxins that were in the brain.
Article:
https://www.sciencealert.com/new-evidence-reveals-an-unexpected-culprit-behind-alzheimer-s-disease
The Study:
Http://advances.sciencemag.org/content/5/1/eaau3333
Edit: Can't seplll
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