Chronic Gingivitis bacteria linked to Alzheimers. Casual link with suggestions of indirect Causation.

JMN

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In Science Advances Jan '19 issue they publish a study which shows that, in mice, the bacteria Porphyromans gingivalis (the same bacteria that causes much chronic gingivitis) produced toxins called 'Gingipains', the bacteria and the toxin were both found in the brain of subjects with oral bacterial load. Administering gingipain inhibitors showed a reduction in neuroinflamation, and the bacterial colony in the brain as well.

Short version: The more oral bacteria, the greater it's toxins, and with the bacterial P. Gingivalis there is proof it and it's toxins have part of causing the brain 'plaques' in Alzheimer's patients.
They found a treatment which was effective in reducing the infection and toxins that were in the brain.


Article:
https://www.sciencealert.com/new-evidence-reveals-an-unexpected-culprit-behind-alzheimer-s-disease

The Study:
Http://advances.sciencemag.org/content/5/1/eaau3333

Edit: Can't seplll
 
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Tayebdental

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Hello sir. And the new studies concluded that gut bacteria communicate with the brain, amazing. As for another choice for teeth cleaning I use the (miswack) it’s been used for thousands of years.
 
JMN

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Hello sir. And the new studies concluded that gut bacteria communicate with the brain, amazing. As for another choice for teeth cleaning I use the (miswack) it’s been used for thousands of years.
You know I'm not a knight, so don't bother with 'Sir' ;)

Can you expand on the miswack? Where do you source the tree sticks? Does it grow locally for you? I understand that it's used like sassafrass twigs, rubbing softened and splayed ends over the teeth, but is there more to it?
 
Tayebdental

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Glenn Kennedy

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It is interesting how this story has been picked up by all of the internet "news" feeds. They are glossing over the fact that the researchers are not sure if the bacteria is a cause or contributor to Alzheimer disease or if Alzheimer patients have gum disease because they are not able to properly care for their gums/ teeth and therefore have more of the bacteria in their system.

The researchers said further studies are needed but hey, they doesn't get the "clicks" as well as headlines that claim the cause of Alzheimer has been found.

Clicker beware.
 
JMN

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It is interesting how this story has been picked up by all of the internet "news" feeds. They are glossing over the fact that the researchers are not sure if the bacteria is a cause or contributor to Alzheimer disease or if Alzheimer patients have gum disease because they are not able to properly care for their gums/ teeth and therefore have more of the bacteria in their system.

The researchers said further studies are needed but hey, they doesn't get the "clicks" as well as headlines that claim the cause of Alzheimer has been found.

Clicker beware.
Yeeap. Which is why I put the real study there in addition to the others. Reading comprehension is getting to sad levels. The difference between casual and causal has been erased in most minds.
 
PDC

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It is interesting how this story has been picked up by all of the internet "news" feeds. They are glossing over the fact that the researchers are not sure if the bacteria is a cause or contributor to Alzheimer disease or if Alzheimer patients have gum disease because they are not able to properly care for their gums/ teeth and therefore have more of the bacteria in their system.
Clicker beware.

Let’s just agree that we should all maintain good oral hygiene just to be safe :

"Our identification of gingipain antigens in the brains of individuals with AD and also with AD pathology but no diagnosis of dementia argues that brain infection with P. gingivalis is not a result of poor dental care following the onset of dementia or a consequence of late-stage disease, but is an early event that can explain the pathology found in middle-aged individuals before cognitive decline," the authors write in their paper.

Last year, a Taiwanese study found that people with a 10-year or longer history of chronic periodontitis (CP) were 70% more likely than people without the condition to develop Alzheimer's.
Another study found people with mild to moderate Alzheimer's who had gum disease experienced a quicker rate of cognitive decline compared with those without.
 

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