Are you asking from 3Shape specifically or in general. Almost all CAM equipment, especially from major manufacturers will accept an .STL (stereolithography) file. In regards to the angle and spruing it depends on which printer you decide to go with. Those like Objet, 3D Systems, and Dimension that use support material are fairly fire and forget as they will develop their own support structure to make sure the object prints correctly. With these printers the biggest thing you want to pay attention to is the height of the job, which controls the time of the build. The taller the job the longer the printer will take to create the part and often the more support material will be used (generally the flatter the object the less support material, though this is not always true). There is also the added cost of the support material, and the labor necessary to reduce it which again varies from system to system. Conversely there are the perfactory style printers like EnvisionTEC that only use a single material type and have sprues that support the object. With this method orientation and support is much more important as if there is an unsupported section of crown it will not print correctly and could fall of the build tray. This means a bit more time in nesting but a somewhat cheaper cost per unit since only a single material is used, and a much faster clean up time (arguable I know). Perfactory machines also have a tendency to be much simpler from a mechanical standpoint which means less parts that can break.
3D Printers will work with any system that can produce an .STL file. Additional some have special agreements, like Sirona and 3D Systems, in which a non-STL file can be used.
Hope this helps. Let me know if you need more info.
